Learning to build and interrogate the pangenome of Brachypodium distachyon
Pangenomes are the union of all genomic sequences known for a group individuals. These can be from different wild populations or diverse cultivars of a crop. Moreover, they often include non-domesticated related species that might provide alleles lost during breeding. Pangenomes are always unfinished, as new data can always be added. In this talk I will review how our community sampled Brachypodium distachyon plants around the Mediterranean, produced whole genome sequences for them and finally learnt, by trial and error, how to extract evolutionary and adaptation information from the resulting pangenome.